In partnership with the Center on the Developing Child at Harvard University, the Massachusetts Chapter of the American Academy of Pediatrics, and Strategies for Children, Boston Children's Museum co-sponsored its second Early Childhood Summit April 5, 2013 at the Federal Reserve Bank in Boston. 400 attendees listened to and participated in presentations on early brain development and the importance of executive function, the effect of stress on children, effective school readiness and family support programs, digital media in children's lives, the critical role of play in early childhood development, and implications for public policy. Leading researchers and professionals in the fields of health, education and business shared their insights, identified best practices, and discussed both the challenges and solutions for enhancing early childhood development opportunities. Video of the plenary sessions is included here as well as the agenda and a link to the Cross-Sector Innovation Session Guides and Readings.